Other Notable Health Studies & Research From May 18, 2022

There are dozens of studies, innovations, and research findings released everyday by institutions and clinics across the world. Here’s a look at some of the other notable health reports from May 18.

Risk factors for dementia may vary with age
A new study shows that among people around age 55, the risk of developing dementia over the next 10 years was increased in those with diabetes and high blood pressure.

NIAID Announces Antiviral Drug Development Awards
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

Navigating Uncharted Territory in Female Brain Aging
Researchers at the University of Arizona Health Sciences Center for Innovation in Brain Science were awarded a $2.7 million MERIT award from the National Institutes of Health’s National Institute on Aging to continue work on the impact of estrogen as a master regulator of the brain’s bioenergetic system, which promotes glucose transport and metabolism and energy generation.

Maintaining normal serum potassium levels in peritoneal dialysis may reduce risk of peritonitis
Hypokalemia is usually present in sufferers on peritoneal dialysis (PD) and related to poor outcomes. A multicenter, open-label, potential, randomized managed trial was carried out in 167 hypokalemic sufferers receiving PD.

CMU and Columbia Researchers Magnify Hidden Biological Structures with MAGNIFIERS
A research team from Carnegie Mellon University and Columbia have combined two emerging imaging technologies to better view a wide range of biomolecules, including proteins, lipids and DNA, at the nanoscale.

Brain Capital: A New Investment Approach for Late-Life Well-Being
Within many societies and cultures around the world, older adults are too often undervalued and underappreciated, according to a new article in the journal Innovation in Aging.

Surveillance pathway tells cells when they run low on lipids
UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

Both nature and nurture contribute to signatures of socioeconomic status in the brain
In a new report in Science Advances, an international research team led by scientists at the University of Pennsylvania and Vrije Universiteit Amsterdam take strides to tease apart the relative contributions of genes and environment.

Childhood circumstances and personality traits are associated with loneliness in older age
Life circumstances during childhood—including having fewer friends and siblings, low-quality relationships with parents, bad health and growing up in a poorer household—are all correlated with a higher rate of loneliness in older age, according to a new study published this week in the open-access journal PLOS ONE by Sophie Guthmuller of Vienna University of Economics and Business, Austria.

Women who embraced their partner subsequently had lower stress-induced cortisol response
Women instructed to embrace their romantic partner prior to undergoing a stressful experience had a lower biological stress response—as indicated by levels of the stress hormone cortisol in saliva—compared to women who did not embrace their partner.

Study in Mice Suggests that COVID-19 Increases Risk of Developing Parkinson’s Disease
Now, Jefferson and collaborators show in a new study performed in mice, that the SARS-CoV-2 virus responsible for the COVID-19 pandemic could increase the risk of brain degeneration seen in Parkinson’s disease.

Aging-US: Hallmarks of Cancer and Hallmarks of Aging Reviewed
In this review, Dr. Blagosklonny expands on Gems and de Magalhães’ notion that canonic hallmarks of aging are superficial imitations of the hallmarks of cancer.

Rutgers Pair Creates Monitoring Toolkit to Speed Production of Biologic Drugs
Two Rutgers engineers specializing in the process of making drugs derived from living organisms have created an analytical tool they expect will accelerate the discovery and production of biologic drugs that are often at the cutting edge of biomedical research.

Choline makes key nutrient available for baby development
The nutrient choline – shown to have long-term benefits for children whose mothers consume it during pregnancy – also helps the body more efficiently use an omega 3 fatty acid that is essential for fetal brain, cognition and vision development, a new study finds.

New Surgical Robot Is Safe and Effective for Localized Prostate Cancer Surgery
A new surgical robotic system is “feasible, safe, and effective” for treatment of early-stage prostate cancer, concludes an initial evaluation in The Journal of Urology®, an Official Journal of the American Urological Association (AUA).

How three mutations work together to spur new SARS-CoV-2 variants
In a new study in ACS’ Biochemistry, researchers examined how these mutations change the way a key piece of the virus functions.

In stop-COVID19 trial, Brensocatib did not improve condition of patients with severe COVID-19
Brensocatib did not improve the clinical status of patients hospitalized with severe SARS-CoV-2 infection in the double-blind randomized, placebo-controlled STOP-COVID19 multicenter clinical trial, according to research published at the ATS 2022 international conference.

Four‑year college students drink more, use marijuana less than community college peers
Students at four-year colleges and universities drink nearly twice as much alcohol as their peers in two-year colleges, according to a survey of college students in the Seattle area.

‘Honey, Don’t Forget the Sunscreen!’ Three Beliefs That Affect Sunscreen Use by Older Adults
Reminders from a romantic partner might be an effective way to encourage sunscreen use by people age 50 or older, suggests a study in the May/June issue of The Journal of the Dermatology Nurses’ Associationofficial publication of the Dermatology Nurses’ Association.

COVID long-haulers: Study shows who is most at risk, impact on local communities
A Japanese research team looking at COVID-19’s lingering impacts on survivors and local communities found that having a mild case of COVID-19, smoking status, comorbidities, or your sex aren’t significant predictors to tell if you are less likely to develop long-term symptoms but age is.

Study shows family medicine physicians face many barriers to providing medical abortions
Doctors cite resistance from institutions and government restrictions that block patients from accessing abortion pills.

Study Finds Kaiser Permanente Initiative Improves Mental Health in Online Gaming Community
A first-of-its-kind mental health initiative developed by Kaiser Permanente and esports organization Cloud9 has been found to be an effective way of supporting the mental health of young adult esports players and fans, according to a new study published today in NEJM Catalyst.

Quantifying the live microbes on your plate
A group of scientists has completed the first large-scale estimate of how many live microbes are consumed by Americans daily.

Imatinib Shows Improved Outcomes for Patients with Severe COVID-19 in the CounterCOVID Clinical Trial
Patients with severe COVID-19 who were given imatinib had lower mortality rates at 90-day follow-up, according to research published at the ATS 2022 international conference.

Leicester health research recognised among best in the UK
Health research enabled by partnership between the University of Leicester and both the University Hospitals of Leicester NHS Trust and Leicestershire Partnership NHS Trust has been recognised among the best in the UK.

Component for brain-inspired computing
Researchers from ETH Zurich, the University of Zurich and Empa have developed a new material for an electronic component that can be used in a wider range of applications than its predecessors.

Cardio-Obstetrics Survey Gives Birth to New Training Needs
Cardiovascular disease is the primary cause of pregnancy‐related death, yet a new national survey led by doctors at the Smidt Heart Institute at Cedars-Sinai suggests that few cardiologists, trainees or care team members are trained in cardio-obstetrics, a specialty that brings together experts from cardiology, obstetrics and primary care.

A new form of therapy for autistic individuals has been evaluated
A doctoral thesis at Karolinska Institutet has investigated whether Acceptance Commitment Therapy (ACT) can be used for individuals with Autism Spectrum Disorder.

“Natural Immunity” from Omicron is Weak and Limited, Study Finds
In unvaccinated people, infection with the Omicron variant of SARS-CoV-2 provides little long-term immunity against other variants, according to a new study by researchers at Gladstone Institutes and UC San Francisco (UCSF), published today in the journal Nature.

Coeliac cereal – Research shows oats could be the answer
Ground-breaking new research published in Nature has decoded the genome of oats and explained why the popular cereal could be suitable for most people with coeliac disease and gluten intolerance.

The oat genome unlocks the unique health benefits of oats
Scientists from Helmholtz Munich, Lund University and the ScanOats network finally elucidated at the genetic level why oats are healthier and cause fewer allergies and intolerances than other cereals.

Oat reference genome: Insights into a uniquely healthy cereal crop
An international research team now presents a high-quality reference genome of A. sativa and its most closely related wild relatives.

New Weight-Loss Intervention Targets Instinctive Desire to Eat
People who are highly responsive to food lost more weight and, importantly, were more successful at keeping the pounds off using a new alternative weight-loss intervention that targets improving a person’s response to internal hunger cues and their ability to resist food, reported a team led by University of California San Diego experts in the May 18, 2022 online issue of JAMA Network Open.

Knowledge of Fertility and Perspectives About Family Planning Among Female Physicians
This qualitative study with structured 1:1 qualitative interviews with 16 female physicians identified fertility and family-building concerns that were used to develop and pilot test a survey for women in medicine.

Routine Surveillance and Vaccination on a University Campus During the Spread of the SARS-CoV-2 Omicron Variant
For the Fall semester (August 26 through December 18, 2021), all undergraduates (15 503 students), 2873 graduate students (28.5%), and 2803 employees (20.9%) were required to register for and participate at least once a week in free, on-campus polymerase chain reaction COVID-19 surveillance testing.

Impor­tant genetic ori­gin of our senses iden­ti­fied
Researchers have deciphered the function of a gene that is essential for the formation of neural structures in the head of vertebrates and their perception of the environment.

Lifestyle coaching lowers blood pressure in Black adults
Culturally tailored lifestyle coaching can help Black adults with hypertension improve their blood pressure control, new Kaiser Permanente research shows.

The Estée Lauder Companies showcases latest data on oxidative damage, skin barrier function, hyperpigmentation, and natural extracts at the 2022 Society for Investigative Dermatology Annual Meeting
The Estée Lauder Companies Inc. (NYSE: EL) research and development (R&D) team will present data that provides new insights in priority areas of research including epidermal function and skin barrier, fermentation, skin aging and pigmentation.

Antioxidant derived from unripe acerola can replace synthetic additive banned in several countries
As part of a search for natural alternatives, researchers at the University of São Paulo (USP) in Brazil have studied phenolic compounds from Acerola cherry (Malpighia emarginata) and extracted antioxidant microparticles as effective as TBHQ from the unripe (green) fruit.

After Sprint for COVID-19 Vaccines, HVTN Researchers Return to HIV Marathon With Fresh Determination and Knowledge, Launch Clinical Research Registry and Ad Campaign
Building on momentum from the highly successful COVID-19 vaccine clinical trials, the HIV Vaccine Trials Network (HVTN) is launching a new HIV awareness campaign and unveiling a first-of-its-kind national registry that will provide updated HIV information and make it easier to learn about and participate in HIV clinical trials at HelpEndHIV.org.

New Recommendations on Mastitis Spectrum from Academy of Breastfeeding Medicine
The Academy of Breastfeeding Medicine (ABM) has released new recommendations for the diagnosis and treatment of the mastitis spectrum.

Preliminary study shows minimally invasive diagnostic biomarker strategy successful in detecting early esophageal cancer
A minimally invasive and low-cost device combined with molecular biomarkers developed by Johns Hopkins Medicine researchers shows a 90% success rate in detecting esophageal cancer.

Researchers discover effective combination immunotherapy for liver cancer
Researchers from the University of Missouri School of Medicine have discovered a specific combination immunotherapy that shows promise in the fight against liver cancer.

Public health “detectives” will track potential links between COVID-19 and poor pregnancy outcomes
Two Medical University of South Carolina researchers in the Department of Public Health Sciences will try to answer those questions with more than $1.5 million in grant funding from the National Heart, Lung, and Blood Institute.

Deciphering the Brain and How the Visual System Processes Information
In the high-speed supercomputer that is the human brain, where quick connections are made in response to outside stimuli, neurons (or individual cells) race to transmit information using electrical signals.

Children’s Hospital Colorado First in the World to Implant Recently FDA-Approved Stent for Treatment of Congenital Heart Disease
Children’s Hospital Colorado (Children’s Colorado) is the first hospital in the world to implant the newly FDA-approved G-Armor Stent. Although the stent is designed to be used in the smallest of patients, it was first implanted in a Colorado father of two.

Ruminating on our ruminations causes more depression
A lot of young people have depressive symptoms. Ruminative thinking, and even thinking about how much you ruminate, reinforces the symptoms.

Penn Medicine Study Reveals Imaging Approach with Potential to Detect Lung Cancer Earlier, at the Cellular Level
Researchers at the Abramson Cancer Center at the University of Pennsylvania  have found a way to identify lung cancer at the cellular level in real time during a biopsy, offering promise in the ability to detect the disease earlier and with more confidence.

Moffitt Researchers Identify Tumor-Based Methylation Patterns as Cancer Biomarkers
In a new study featured on the cover of the May 1 issue of the journal Cancer Research, Moffitt Cancer Center researchers report on their identification of biomarkers based on a type of genetic modification called methylation that predicts the type of tumor immune environment and patient outcomes.

Healthy diet helps obese people with chronic inflammation and skin wound healing
In a study recently published in the journal Theranostics, the scientists investigated how saturated fatty acids contribute to the increased occurrence of inflammation or disrupt wound healing.

A novel optogenetic tool for precise control of Gq signaling
Ruicheng Dai, Tao Yu, Danwei Weng, and their colleagues in Luo’s group determined to develop an optogenetic tool for precise control of intracellular Gq signaling.

Memorial Sloan Kettering Cancer Center Study Points to Expanded Genomic Testing that Aims To Benefit Children and Young Adults With Cancer
New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, and young adult patients with solid tumors.

Health screening, genetic tests might identify people at risk of premature heart disease
Health screening and genetic tests might identify more than 1 million U.S. adults who carry a gene for familial hypercholesterolemia, a common genetic disorder that causes elevated low-density lipoprotein (LDL) cholesterol, known as “bad cholesterol,” which may lead to premature heart attack or death, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

On the trail of urinary tract infections
The German government is providing about 2.4 million Euros for a new research group in infectious diseases at JMU Würzburg. Dr. Carmen Aguilar will use this grant to search for new therapeutic approaches against one of the most common and recurrent bacterial infections.

Researchers find new approach to treating cardiovascular diseases
A specific protein in blood vessel cells plays a major role in the development of vascular and cardiovascular diseases: The presence of too many “thromboxane A2 receptors” hinders the formation of new blood vessels.

Dopamine makes you feel happy. But we probably have to be rewrite the textbooks
A team of researchers at the University of Copenhagen has discovered a new piece in the puzzle of the brain’s ‘feel good’ substance, dopamine.

Viral infections during pregnancy affect maternal care behaviour
A preclinical study has now shown, for the first time, that a viral-like immune activation during pregnancy also affects the maternal brain and significantly disrupts maternal care behaviour after the birth.

Do early therapies assist very younger youngsters with or at excessive chance for autism?
In an evaluation of opinions revealed between 2009 and 2020 that assessed therapeutic or academic interventions for very younger youngsters with or at excessive chance for autism, researchers discovered that sure sorts of interventions—referred to as naturalistic developmental behavioral interventions, developmental interventions, and behavioral interventions—can present advantages, however there have been vital limitations within the high quality of the proof and lots of variations in how research had been carried out.

Does a home-based exercise program benefit patients after hip fracture surgery?
A study published in the Journal of the American Geriatrics Society indicates that a 12-month home-based progressive and supervised exercise program can help to improve functioning and physical performance after patients undergo hip fracture surgery.

Potential Pitfalls of High-Risk Prescribing Practices in Older Adults
In a new study published in Geriatrics and Gerontology International, a research team led by the University of Tsukuba evaluated the relationship between high-risk prescribing practices and the risk for disability in people aged 65 years and older.

A new way to combat SARS-CoV-2: Using a desktop-sized air-curtain to inactivate almost 100% of coronavirus particles
By combining medical and engineering technologies, a team of Nagoya University researchers combined a desktop-sized air-curtain with LEDs to irradiate the virus and allow people to interact in close environments safely.

New research maps how the brain changes during depression treatment
For the first time, researchers have shown what happens to the brain when a person receives a depression treatment known has repetitive transcranial magnetic stimulation (rTMS).

‘5 to over 50 days’ significant improvement in 10㎚ thick artificial cell membrane stability
The Korea Institute of Science and Technology (KIST, President Seok-Jin Yoon) announced that the research team led by Dr. Tae Song Kim of the Brain Science Institute has succeeded in developing an artificial cell membrane that can be kept stable for over 50 days on a silicon substrate.

App to enable early diagnosis and intervention for speech impairment
Curtin researchers will investigate the use of a web-based assessment application for the early and accurate detection of speech impairment, as part of a new Curtin-led project that has been supported by the Federal Government.

Reliable diagnostics at the tip of your finger
Biomarkers are components that may be present in biological samples and are related to specific diseases. Therefore, doctors can analyze biological samples from a patient to check their health condition or to monitor the progress of a specific therapy.

Energy-Efficient AI Hardware Technology Via a Brain-Inspired Stashing System​
The research group led by Professor Kyung Min Kim from the Department of Materials Science and Engineering has developed a technology that can efficiently handle mathematical operations for artificial intelligence by imitating the continuous changes in the topology of the neural network according to the situation.

Timing of heart surgery crucial, research shows
Valve replacement heart surgery should be performed earlier than conventionally thought for people with aortic stenosis – according to new research from the University of East Anglia.

City of Hope and Imugene Announce First Patient Dosed in Phase 1 Trial to Test Cancer-Killing Oncolytic Virus Against Solid Tumors
Imugene Limited (ASX:IMU), a clinical-stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

Pollution responsible for nine million deaths in 2019, with little progress in four years
The new report is an update to The Lancet Commission on Pollution and Health [1], published in The Lancet Planetary Health, and states that although the number of deaths from pollution sources associated with extreme poverty (such as indoor air pollution and water pollution) have decreased, these reductions are offset by increased deaths attributable to industrial pollution (such as ambient air pollution and chemical pollution).

Substudy of ADVOCATE trial for ANCA-associated vasculitis finds avacopan reduces need for glucocorticoids, respiratory and ENT involvement
Avacopan was better than prednisone in reducing respiratory as well as ear, nose and throat (ENT) involvement and enabled reduced glucocorticoid use in ANCA-associated vasculitis patients participating in the phase 3 ADVOCATE trial.

Where Does Vaccine Hesitancy Exist? USC AI Researchers Can Predict on the Zip Code-Level, in Real-Time
In a new paper published in PLOS Digital Health, researchers at the USC Viterbi School of Engineering proposed a natural language processing (NLP) software that learns where skepticism surrounding vaccines lives in real-time.

Texas A&M AgriLife describes new protein structures to aid rational drug design
In a major advance for rational drug design, a Texas A&M AgriLife team has described several protein structures of a crucial player in cellular processes.

Aging well in a pandemic: Older adults share what it takes
Despite the pandemic’s terrible toll on older adults, a new national poll shows that most people over 50 say their health is as good as it was before March 2020, or even better.

Rice chemists skew the odds to prevent cancer
Rice chemist Anatoly Kolomeisky, lead author and postdoctoral researcher Hamid Teimouri and research assistant Cade Spaulding are developing a theoretical framework to explain how cancers caused by more than one genetic mutation can be more easily identified and perhaps stopped.

Awardees named for $20 million project to foster diversity in clinical trial research
Teams of research scientists from 11 universities and health care systems will lead a ground-breaking $20 million research project to study the barriers to ensuring people of diverse race and ethnicity are represented and included in clinical research trials, identify best practices to overcome those barriers and determine how solutions can be implemented across the research community.

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