Other Notable Health Studies & Research From May 9, 2022

There are dozens of studies, innovations, and research findings released everyday by institutions and clinics across the world. Here’s a look at some of the other notable health reports from May 9.

Two Brigham scientists honored for their work on gene and cell therapies
At the 2022 World Medical Innovation Forum, Mass General Brigham investigators presented their high potential new technologies as part of the “First Look: New Gene and Cell Therapy Technologies” session.

Hypertensive pregnancy disorders linked to higher risk of cardiac events later in life
Women with hypertensive disorders of pregnancy (HDP), such as gestational hypertension or preeclampsia, are at a higher risk for developing cardiovascular disease (CVD) later in life.

Racial Gap in Completed Doctor Visits Disappeared in 2020 as Telemedicine Adopted
Historically, there has been racial inequity when it comes to primary care appointments, which are vital for managing and preventing chronic disease.

Nonlethal parasites reduce how much their wild hosts eat, leading to ecosystem effects
A new study led by Washington University in St. Louis uses a mathematical model and a global meta-analysis to highlight the cascading consequences of common parasitic infections in wild animals on terrestrial ecosystems.

Quantifying Cognitive Decline in Dogs Could Help Humans With Alzheimer’s Disease
Researchers have found that a suite of complementary tests can quantify changes in dogs suspected of suffering from cognitive decline.

Hypertensive pregnancy disorders linked to future cardiac events
Women who experienced complications related to developing high blood pressure, or hypertension, during pregnancy had a 63% increased risk for developing cardiovascular disease later in life, according to research funded by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.

Text messaging program linked to improved lifestyle risk factors for heart attack survivors
A text messaging program successfully supported, informed and motivated people after a heart attack on how to prevent a second heart attack, according to new research published today in the American Heart Association’s flagship, peer-reviewed journal Circulation.

COVID-19 has negatively impacted how auditors work
COVID-19 has disrupted financial statement auditing globally and impacted group dynamics in an industry vital to the health of the economy, according to a new study.

Gene Therapy Shows Promise in Treating Neuropathy from Spinal Cord Injuries
An international team of researchers, led by scientists at University of California San Diego School of Medicine, report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries.

Scientists identify a new drug that halts recurring brain tumor growth
When a non-metastatic brain tumor—a meningioma—recurs after surgery and radiation treatment, a patient is out of options.

Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer
Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children.

Moffitt Researchers Identify Key Factors Impacting Adaptive Therapy
Researchers in the Center of Excellence for Evolutionary Therapy at Moffitt Cancer Center have been investigating an alternative treatment approach called adaptive therapy that focuses on maintaining disease control instead of complete tumor cell elimination.

Effects of Breastfeeding on Maternal Mental Health
A new systemic review of the literature examines the effects of breastfeeding on maternal mental health to inform breastfeeding recommendations.

T Cell Behavior Determines Which Tumors Respond to Treatment
When immune cells called T lymphocytes infiltrate malignant tumors, the genetic program of those T cells and the developmental path they then follow, may affect their response to immunotherapy and predict overall patient survival, according to a new study by Weill Cornell Medicine investigators.

Multi-Tasking Wearable Continuously Monitors Glucose, Alcohol, and Lactate
Engineers at the University of California San Diego have developed a prototype of such a wearable that can continuously monitor several health stats—glucose, alcohol, and lactate levels—simultaneously in real-time.

Target to make immunotherapy for cancer safer, while more effective
Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body’s immune system to kill cancer.

Targeting interleukin-6 could help relieve immunotherapy side effects
Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

Racial and Ethnic Disparities in Estimated Excess Mortality From External Causes in the US, March to December 2020
COVID-19 has disproportionately affected racial and ethnic minority groups in the US. However, estimating the full effects of the pandemic on health disparities should account for other causes of death, including external causes.

Risk Factors Associated With Alzheimer Disease and Related Dementias by Sex and Race and Ethnicity in the US
In this cross-sectional study, the modifiable risk factors most prominently associated with ADRDs were midlife obesity, physical inactivity, and low education.

Differences in Outcomes and Factors Associated With Mortality Among Patients With SARS-CoV-2 Infection and Cancer Compared With Those Without Cancer
In this systematic review and meta-analysis of 81 studies involving 61 532 patients with cancer, patients who were younger, had lung cancer, or had hematologic cancer were at an increased risk of mortality from COVID-19.

“New and Improved” Supermarkets Trim Childhood Obesity in NYC
Access to newer supermarkets that offer fresh foods in some of New York City’s poorest neighborhoods was linked to a 1% decline in obesity rates among public school students living nearby, a new study shows.

Drugs showing promise in cancer trials reduce scarring for scleroderma, study shows
Epigenetic drugs that have shown promise in cancer trials significantly reduce scarring in the cells of patients with scleroderma, an incurable and life-threatening autoimmune disease, a new study shows.

Stopping lung damage before it turns deadly
If you’ve ever struggled to breathe, you’ve had a moment of hypoxia—a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an “initial insult.”

Using Virtual Reality for Anger Control
An immersive virtual-reality anger control training program can reduce the level of anger provoked, according to a new study published in the peer-reviewed journal Cyberpsychology, Behavior, and Social Networking.

Experts seek uniform patient confidentiality policies for adolescents
paper published May 9 in Pediatrics outlines how laws concerning adolescent patient confidentiality and independent adolescent consent for health care services vary substantially from state to state, are often unclear, and often run counter to patient confidentiality standards advocated by medical societies.

Postpartum Depression Increased During Pandemic’s First Year, Study Finds
Postpartum depression symptoms increased among U.S. women during the first year of the COVID-19 pandemic, a new UVA Health study reveals.

Researchers identify key epigenetic markers in vulnerability to developing food addiction
A team of researchers has identified in rodents and humans common epigenetic mechanisms related to food addiction.

SDSU Researchers Identify Rare Genetic Markers of Drug-Resistant Tuberculosis
Now, researchers at San Diego State University and their colleagues have identified rare genetic markers in M. tuberculosis that could improve early detection of drug-resistant strains of the disease, helping prevent their spread.

COVID-19 pandemic led to increase in loneliness around the world
People around the world experienced an increase in loneliness during the COVID-19 pandemic, which, although small, could have implications for people’s long-term mental and physical health, longevity and well-being, according to research published by the American Psychological Association.

‘Star Wars’ inspires a young PhD student at the Universitat Politècnica de València in the fight against cancer
The researcher Pilar Baldominos, who is currently pursuing her Universitat Politècnica de València PhD at Harvard University’s Dana-Farber Cancer Institute, has completed a study on the defence mechanisms used by some tumour cells to defeat both the immune system and immunotherapy.

More Coronary Disease Among COPD Patients
Previous registry studies have given reason to suspect COPD patients more often have coronary disease than what can be expected from smoking habits, gender, and age.

Discovery and characterization of naturally occurring chalcones as potent inhibitors of bile salt hydrolases
Bile salt hydrolases (BSHs) play crucial roles in the deconjugation of conjugated bile acids and therefore are key targets for modulating bile acid metabolism.

Food insecurity risk related to diabetes later in life
Young adults who were at risk of food insecurity had increased incidence of diabetes 10 years later, according to a Washington State University study.

Heart Failure 2022: improving outcomes for all patients with heart failure
Heart failure presents differently in women and men – discover the latest evidence and its impact on management at Heart Failure 2022, a scientific congress of the European Society of Cardiology (ESC).

New therapy shown to be effective in women with fibromyalgia and depression
Fibromyalgia is a rheumatic disease of unknown origin, which is characterized by chronic pain and often accompanied by symptoms of depression. It mainly affects women, and there is no cure, but various treatments can help relieve the symptoms.

Getting Sticky with It: Phospholipid Found to Play a Key Role in Epithelial Cell Adhesion
Japanese scientists have now identified the role of PIP2, a phospholipid, in maintaining epithelial cell-cell adhesion and cellular identity.

Investment, action urged to improve access, quality and equity in women’s heart health
Investing in and improving research, awareness and equity in women’s heart health are critical for the health and well-being of women, according to a new Presidential Advisory from the American Heart Association, published today in the Association’s flagship journal Circulation.

SU study sheds light on treatment of hyperkalaemia
​Medical specialists urgently need more knowledge on how to treat and manage hyperkalaemia (too much potassium in the blood), which may cause respiratory muscle weakness and potentially fatal heart rhythm disturbance.

Development of an ensemble model to anticipate short-term COVID-19 hospital demand
In this study published in the journal PNAS, scientists from the Mathematical Modeling of Infectious Diseases Unit at the Institut Pasteur identified the most relevant predictive variables for anticipating hospital demand and proposed using an ensemble model based on the average of the predictions of several individual models.

Brain Size Determined The Chances of Survival Among Large Animals
The researchers link the size of the brain (in relation to the body size of each species) to intelligence, concluding that a large brain, which indicates – in comparison to different species of animals – relatively high intelligence, helped the extant species adapt to changing conditions and cope with human activities such as hunting, which has been a major cause of extinction.

A better diet helps beat depression in young men
Young men with a poor diet saw a significant improvement in their symptoms of depression when they switched to a healthy Mediterranean diet, a new study shows.

A third of Canadians who die in accidental drownings have pre-existing medical conditions like seizures: study
A study looking at a decade of accidental drownings in Canada has found that one in three people who drowned had a pre-existing medical condition — and in almost half the cases, their condition contributed to why they drowned, a worrying statistic that the public needs to be more aware of, researchers say.

Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration
The Enhanced Permeability and Retention (EPR) effect is a golden strategy for the nanoparticle (NP)-based targeting of solid tumors, and the surface property of NPs might be a determinant on their targeting efficiency.

Major discovery provides new hope for blood cancer patients
South Australian scientists have made a significant breakthrough in overcoming drug resistance in acute myeloid leukaemia (AML), a rare and devastating blood cancer that kills most patients within a few years.

Usefulness of Monitoring IgG against Antigen-85B for Prediction of Tuberculosis Development from Latency: from an Elephant Tuberculosis Analysis
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb); the leading cause of human death due to a single pathogen before the emergence of SARS-CoV-2.

Researchers discover a novel approach that could lead to the treatment of devastating brain tumours
Findings from a seven-year research project suggest that there could be a new approach to treating one of the most common and devastating forms of brain cancer in adults – Glioblastoma Multiforme (GBM).

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